Even though a lot of sad shit happens within the universe of Bubblegum Crisis, I don't feel like the series is negative. Maybe it's the bright 80s candy colors or the cheery, upbeat music, but it never seems pessimistic, even if an episode ends on a downer, like yesterday's "Tinsel City" or the follow-up episode, "Born to Kill."
That being said, it is ridiculously difficult to find a happy moment, let alone the happiest one. There are little bits that make me laugh or leave me feeling like something good is going to happen eventually, but I can't recall a moment where I generally felt good about the world. So I had to go back and watch the only episode that I remember ending on a happy note: "Scoop Chase."